In Transformers: Decepticons, Optimus Prime lands on Earth along with the other Autobots to stop the Decepticons. Optimus does not appear until Megatron is released and Starscream escapes with the Allspark. Optimus fights Megatron, but is defeated and is killed while Megatron gives chase to his traitorous second-in-command. In the 2009 Revenge of the Fallen video game by Activision, Optimus Prime is among the playable characters.
The TakaraTomy "Autobot Alliance" release of this toy has some significant differences, including casting the red plastic in a darker shade, making his shin and wheel joints grey rather than Hasbro's bronze, painting the Matrix of Leadership silver, and swapping out the dual energon swords for battle hooks, similar to 2010's Leader class Optimus Prime. However, due to the Japanese release retaining the Hasbro packaging, the box still advertises the dual energon swords rather than the hooks. He retains the masked face used for the Hasbro release.