In "Sick Mind", Optimus is infected with the life-threatening Cybonic plague, prompting Arcee and Bumblebee to infiltrate the Nemesis to find a cure for the virus Megatron himself created. As Optimus grows weaker, he learns of Megatron's survival of the space bridge explosion. It was Bumblebee entering Megatron's mind via cortical psychic patch and retrieving the cure that saved Optimus. In the next episode, "Out of His Head", Optimus is, surprisingly, saved by the revived Megatron when he intercepted Starscream's attempted nosedive to kill him.
Many of the small features and electronics of the original Masterpiece mold are left out. Instead, this Convoy features better overall cartoon accuracy (chest interior, head, etc.), an extensive red paint job that covers much of his red plastic, corrected robot mode proportions, improved articulation, and its gun can now collapse and store inside a compartment on its back in either mode. In addition to Convoy's trailer, which can transform into Combat Deck, it also comes with Roller, a small Spike Witwicky figurine, a die-cast metal Matrix of Leadership (with a clear blue plastic center), and an energy axe that slips over Convoy's right hand. Spike can fit inside the cab in vehicle mode, ride in Roller's seat, or fit into any of the seating compartments inside Convoy's trailer. Roller has options to plug in Convoy's gun or pull Convoy's trailer, and the trailer itself can store Convoy's weapons in any mode. Although not easily breakable, care must be taken for posing the index fingers; extending the finger even far would cause it to pop off.
_{This Wal*Mart-exclusive two-pack pairs the deluxe-size Classics Optimus Prime figure with live-action movie line's Fast Action Battlers Power Hook Optimus Prime toy. Both toys are identical to their original releases, and together represent the Optimus Primes of the oldest and newest generations (at the time) of Transformers, respectively. The movie Prime is designated "2007 Optimus Prime", while the Classics figure is dubbed "1984 Optimus Prime" (referring not, of course, to the toy, which was produced in 2006, but to the character).}
Prime was perpetually at the forefront of the action throughout the early years of the war on Earth, usually confronting Megatron, though in some rare instances, such as against the Insecticon-controlled Decepticons or the Combaticons, teaming up with him for the greater good. He has suffered his fair share of battlefield scrapes, almost meeting his end when his vital cosmotron component was critically damaged by the Decepticon jets and when Laserbeak had his body disassembled and turned into Decepticon trophies, such as a pet "alligaticon" and a defense laser.

Hero Optimus Prime was the first new-mold Optimus Prime toy in the Generation 2 line. He transforms into a Kenworth truck of unknown model with a flatbed trailer. The truck and trailer form his robot mode, but cannot disconnect. His primary gimmick is an air-powered missile launcher that uses an air bellows attached by hose to launch his large, hollow, soft-rubber-tipped missiles. The bellows and missiles attach to his back in robot mode. His rifle plugs into the launcher's main body in truck mode.

Optimus and Prowl received message from Skyfire of a coal transport in Africa, and discovered Megatron was using human slaves. Megatron detonated his coal mines with the world's largest explosion, killing the humans and forging the world's largest diamond — that he would use to as a lens for a satellite to focus the Sun's beams, melting the Rocky Mountains! Prime ordered Skyfire to attack the satellite, and Ratchet to build a square mile panel of metal to deflect the beam, blowing the satellite up. Satellite of Doom The Decepticons attempted to drain the Prudhoe Bay oil reservoir, causing volcanic eruptions and Russia to approach America, accelerating tensions between the countries. Optimus ordered razon gas to be pumped into the reservoir, returning the oil below and raising the Decepticons' aquatic drill. When Continents Collide
^{The 1992 and 1993 European and Canadian releases make up what is often called "Generation 1.5", much to the annoyance of many UK fans. These toys are similar in design to the Generation 2 Transformers, having lightpipe eyes, and pastel colors. The 1993 European figures used the G2 faction symbols which Hasbro UK designed because their licence on the G1 symbols had expired. The 1993 figures were repackaged for European G2 release in 1994, and three subgroup molds got used in the US G2 line.
When we are young, we do not know the value of money let alone the toys we play with. Our parents work tirelessly to buy us the newest, most popular toys and we never realize the effort that went into earning that money. Eventually we get our own jobs and have our own kids. The prices of the toys we had as kids comes as a shock. $150 for a toy? $200 for a toy? These prices are outrageous. It is supposed to be a kid’s toy right? Our eyes may be drawn to the large sets but that doesn’t mean that reasonably priced sets are not nearby. In addition, as I stated before, LEGO has started to market some of their sets to an older audience. That $400 Super Star Destroyer is not for your kid; it is for you. This market didn’t exist 20 years ago.}

In the animated series, Optimus Prime was originally in the Autobot Academy and friends with Sentinel Prime and Elita One. When Elita is lost on a planet dominated by giant spider-like aliens, he blames himself for leaving her behind, where she supposedly dies in the explosion of a wrecked Decepticon warship loaded with Energon. Sentinel doesn't forgive him for losing her and Optimus takes full responsibly for Elita's demise. Ultra Magnus, who had high hopes for him, expels him and thus bars him from any position of the Elite Guard. However, Magnus pulls some strings so that Optimus could be captain of a strange Space Bridge repair crew composed of an old grumbler of a war vet named Ratchet, a fledgling Bumblebee, and his fellow cadet, Bulkhead. Optimus is given command of the starship Omega Supreme.

This increase in average piece count could be a factor in why LEGO is perceived to be more expensive now than in the past. LEGO sets have become larger and more complex. They have started to market directly to an older crowd with sets such as the Modular Buildings and the Architecture series. These new sets have rekindled interest in LEGO for an older generation but at the same time, it has introduced this same generation to the relatively high price of LEGO sets.

IDW's Transformers Collectors Club exclusive comic story, Revelations part 6, is set after the defeat of Galvatron, but before Optimus Prime's mission to start a new Space Bridge project. In this story, the Autobots from the IDW series Robots in Disguise, Optimus Prime, Ultra Magnus, Sentinel Maximus, Downshift, Perceptor, Alpha Trion, Over-Run, Anti-Blaze, Checkpoint, and Scythe, meet the Autobots from the animated series, Cybertron Optimus Prime, Jetfire, Override, Scattorshot, Red Alert, Hot Shot, Lori, Bud, and Coby Hansen, and thank each other and remembering those who were lost in the battles.[40]

This set's Optimusses are based on the Prime incarnation. The larger Optimus is a smaller, simpler build than the first big kit, and makes use of ball-and-socket parts for increased articulation. It also carries a spring-loaded missile launcher. The Optimus Kreon's tampographs are based directly on the Prime cartoon model, though he carries an energon axe akin to the one from the War for Cybertron games. He also has a clear-blue extra "energon" torso piece.

It should be noted that in the lead up to the premiere of the Japanese translation of this series, TakaraTomy marketing director Masahiko Yamazaki indicated changes would be made to place it as a prequel to the 2007 Transformers live-action film. This would have made this version of Optimus Prime an earlier version of the film character. In practice however, the only changes that were made consisted of trimming for time to allow additional promotional material to be added to the start and end, and the name change of Bulkhead into "Ironhide" (with Ironhide becoming "Armorhide"). The future 22nd century Detroit setting and characterizations of the cast remain as they were in the original production.
Once combined, DaiKenzan has three new phrases (spoken in Kenzan's voice), while DaiGekisou has four (in Gekisoumaru's voice). In either combined form, pressing and holding the button activates an additional, longer phrase for their "final attack". DaiGekisou is armed with a scissors-esque "shuriken" made from combining Optimus Exprime's two swords, while DaiKenzan simply wields them separately.

Leader class figure, this is his form used in the Cybertron television series. Can combine with Leobreaker (or Nemesis Breaker) and/or Cybertron Wing Saber, and can use Metroplex's axe or Vector Prime's sword. At first, Optimus Prime's (Galaxy Convoy in the Japanese version) alt-mode is a futuristic firetruck, although some believe it to be some sort of mobile weapons platform (the show itself treats it as a firetruck). This can also transform into a wing mode, with wings and cannons on each side of the truck. In addition to his standard robot mode, he can combine with his rear 'trailer' section to form a heavily armed super mode. That trailer section can also form an independent weapons platform, usable by anyone. His face, designed in the classic Prime style, merges the two mouth-plate elements - a slitted version to expose his mouth, like Beast Wars Optimus Primal did on the television series and a full mouth-plate which can rise to cover it.[60]

Voyager Optimus Prime is a redeco of the toy from the first movie's toyline. Like several redecos or retools of 2007 movie toys, there has been some effort to make this release noticeably different from the previous releases, though the toy ends up looking less accurate to the actual movie appearance than those previous releases. Optimus Prime has a sort of faded Autobot logo on the side of the truck's bunk, and kanji (Chinese characters) on the roof (ending up on his knee in robot mode.) The word "上海将军" means "Shanghai General", while "大将" means "Grand general".
In Transformers: The Last Knight, he is brother-in-arms with Bumblebee who he fought alongside with to foil the Nazi Party in World War 2. He speaks with a thick French accent due to being stuck in France for so long, much to his own embarrassment. He wields a special gun which can briefly slow down time. He is also the only Transformer who is shown to speak in vehicle mode. [20][21]
Hot Rod is often portrayed as energetic, yet brash and headstrong, with an overwhelming self-confidence that borders on arrogance.[1] As Rodimus Prime, leader of the Autobots, he is significantly more mature, physically powerful and instilled with the wisdom of the previous holders of the Matrix of Leadership. In a reversal of his behavior as Hot Rod, Rodimus is plagued by lack of confidence in his role as Autobot commander and often doubts his own decisions, feeling both inferior to and in some ways living in the shadow of the previous leader of the Autobots, Optimus Prime.
Part of the first wave of TakaraTomy Lost Age: Movie Advanced toys, this Japanese-exclusive redeco of 2007 Transformers Protoform Optimus Prime is given a Generation 1-styled color scheme (which is also based on his appearances in IDW's Transformers: Foundation comic-book mini-series). Protoform Optimus Prime transforms into his "entry" mode. This mode somewhat resembles a cybertronic truck, with false wheels sculpted onto the sides, and Optimus Prime's trademark windows in front. His now-blue flame decoration piece fits to the back of the "vehicle", creating the illusion of a flaming comet's tail (Not sure if this was mean to represent his jetpack blast effect or his atmospheric entry heat effect, which is for no reason: entirely blue instead of hot red). The bottom of the vehicle has small wheels to roll the toy across smooth surfaces.