Optimus Prime is one of the playable Autobot characters in the 2010 video game Transformers: War for Cybertron. In the Autobot campaign, he starts off as Optimus, a warrior who rallies his fellow autobots against the Decepticons following the reported death of their leader Zeta Prime. He succeeds in defending the Autobots' home city of Iacon from Starscream and his forces. Optimus then receives a distress call from Zeta Prime. Knowing that this is most likely a trap set by Megatron, he proceeds anyway with a rescue mission. He lets himself, Bumblebee, and SideSwipe be captured by the Decepticons and is sent to a prison in Kaon, the decepticon capital, in an elaborate scheme to free Zeta Prime and all imprisoned Autobots. He frees all the other prisoners, and defeats Soundwave and his minions Frenzy, Rumble, and Laserbeak, but he is too late to save Zeta Prime. After taking Zeta Prime's body back to the Autobot high council, he is bestowed upon the well earned title of Prime.
Simon Furman's "Alignment", a text story available through Transforce, a British Transformers convention, mentions Prime falling during what was intended to be the final conflict with the Decepticons at Pinea Omicron, long after the events of the Generation 2 comic book. He managed to defeat Galvatron II, but in doing so, was damaged such that Grimlock had to engage a stasis field around him to save his flickering Spark, making Prime a living war monument.
Transformers GT "GT-R Prime" is a heavy retool of Alternity Convoy, transforming into a 1:32 replica of the Motul Autech GT-R race car used by the Nismo team in the Super GT racing championship series. He retains the flip-out blasters of the Alternity toy and can also wield his new Impact Wrench Gun accessory (also called the "Optimus Rifle" on the Transformers GT website), a weapon based on the impact wrenches used in car repairs. Like all GT toys, Prime also comes with a GT Sister, poseable human figures themed after race queens, his partner being a lady named Misaki.
MP-10 Convoy, advertised as a "perfect new model" on its packaging, is an entirely new tooling of Generation 1 Optimus Prime. Convoy is now smaller, making him more in-scale with other recent Masterpiece toys, such as Rodimus, and comes with a trailer and various accessories. While the front of the vehicle mode's cab is an accurate depiction of a mid-to-late-1980s Freightliner FLT cabover, the back half, (which is, as usual, made out of Convoy's legs) is much larger and robot-leggier in proportion. (So much that they sculpt a ladder on each side.)
A (technically) unreleased "black" redeco of Henkei Voyager-sized Convoy using the same plastic layout and paint mask but replacing red and blue with black, silver with gray, leaving the previously vacuum-metalized grill/fender area unpainted, changing the blue tint for the windows to red and changing all silver and yellow paint operations to blue. The red Autobot insignias would have remained unchanged.
Originally, Optimus Prime was created as the leader of the Autobots, though it is unknown how he was created or his origins. In a possible future, Megatron was threatened by the existence of the Aerialbots and had Shockwave build a time machine to send them back in time to get rid of them. However, he only ended up changing history for the better. In the revised timeline, Optimus Prime began his life as a robot named Orion Pax, a mostly defenseless dock worker during the Golden Age of Cybertron nine million years ago, with a girlfriend named Ariel and a best friend named Dion. During this time, a new breed of robot with new flight capabilities appeared on the planet that Orion idolized. When Megatron, the leader of the new group of robots, approached him with inquiries about using one of the dock warehouses, Orion was swayed by Megatron. Both Orion and Ariel were severely wounded when Megatron and his forces attacked in order to claim the energy stored there. Searching for someone to help them, the time-displaced Aerialbots took Orion and Ariel to the ancient Autobot, Alpha Trion, who used them as the first subjects for the new reconstruction process he had developed involving rebuilding the frail Autobot frames into more battle-hardy configurations.